Dept. Immunobiology IDAC, Tohoku University


1. Inamori K, Togashi Y, Fukuoka S, Akagi K, Ogasawara K, Irie T, Motooka D, Kobayashi Y, Sugiyama D, Kojima M, Shiiya N, Nakamura S, Mariyama S, Sizuki Y, Nishikawa H. Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer. JCI insight 2021 in press.

2. Ueda T, Sato N, Koizumi R, Ueda K, Ito K, Ogasawara K, Narushima T. Formation of carbon-added anatase-rich TiO2 layers on titanium and their antibacterial properties in visible light. Dent Mater 2020, in press.

3. Furukawa M, Ito S, Suzuki S, Fuchimoto D, Onishi A, Niimi K, Usami K, Wu G, Bazer FW, Ogasawara K, Watanabe K, Aso H, Nochi T. Organogenesis of ileal Peyer’s patches is initiated prenatally and accelerated postnatally with comprehensible proliferation of B cells in pigs. Front. Immunol., 11: 604674, 2020

4. Kosuge M, Furisawa-N E, Ito K, Saito Y, Ogasawara K. Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses. Scientific Reports 10, 17766,, 2020.

5. Tashiro R, Niizuma K, Khor S, Tokunaga K, Fujimura M, Sakata H, Endo H, Inoko H, Ogasawara K, Tominaga T. Identification of HLA-DRB1 04:10 allele as riskallele for Japanese moyamoya disease and its association with autoimmune thyroid disease:A case-control study. PLoS One. Aug 14;14(8):e0220858. doi: 10.1371/journal.pone.0220858, 2019

6. Sitalaksmi RM, Ito K, Ogasawara K, Suto Y, Itabashi M, Ueda K, Hirasawa N, Narushima T, Hendrijantini N, Kresnoadi U, Sasaki K. COX-2 induces T cell accumulation and IFN-γ production during the development of chromium allergy. Autoimmunity Vol. 52 (5-6), 228-234, 2019.

7. Gokcekaya, O., Ueda, K., Ogasawara, K., Narushima, T. Antibacterial activity of Ag nanoparticle-containing hydroxyapatite powders in simulated body fluids with Cl ions. Materials Chemistry and Physics, 223, pp. 473-478, 2019.

8. Ueda, T., Ueda, K., Ito, K., Ogasawara, K., Kanetaka, H., Mokudai, T., Niwano, Y., Narushima, T. Visible-light-responsive antibacterial activity of Au-incorporated TiO2 layers formed on Ti–(0–10)at%Au alloys by air oxidation Journal of Biomedical Materials Research - Part A, 107 (5), pp. 991-1000, 2019.

9. Onodera R, Asakawa S, Segawa R, Mizuno N, Ogasawara K, Hiratsuka M, Hirasawa N. Zinc ions attenuate Ni ion-induced inflammation Scientific Reports Volume 8, Issue 1, December 1 Article number 2911, 2018.

10. Takeda Y, Suto Y, Ito K, Hashimoto W, Nishiya T, Ueda K, Narushima T, Takahashi T, Ogasawara K. TRAV7-2*02 Expressing CD8⁺ T Cells are responsible for Palladium allergy Int J Mol Sci. 18(6): 1162, 2017.

11. Ito K, Nakajima A, Fukushima Y, Suzuki K, Sakamoto K, Hamazaki Y, Ogasawara K, Minato N, Hattori M The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine. PLoS One. 12(3):e0173629, 2017.

12. Kawakami T, Ito K, Matsuda Y, Noda M, Sakurada A, Hoshikawa Y, Okada Y, Ogasawara K. Cytotoxicity of natural killer cells activated through NKG2D contributes to the development of bronchiolitis obliterans in a murine heterotopic tracheal transplant model. Am J Transplant. 17(9): 2238-2349, 2017.

13. Takeda K, Nakayama M, Hayakawa Y, Ogasawara K, Okumura K, Kojima Y, Ikeda H, Imai N, Thomas D, Smyth M. IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting Nature Communications 8:14607, 2017.

14. Iguchi N, Takeda Y, Sato N, Ukichi K, Katakura A, Ueda K, Narushima T, Higuchi S, Ogasawara K The antihistamine olopatadine regulates T cell activation in palladium allergy International Immunopharmacology 35:70-76 2016.

15. Nakamura K, Kawakami T, Yamamoto N, Tomizawa M, Fujiwara T, Ishii T, Harigae H, Ogasawara K. Activation of the NLRP3 inflammasome by cellular labile iron. Exp Hematol. 44(2):116-24, 2016.

16. Maruyama T, Kobayashi S, Ogasawara K, Yoshimura A, Muta T, Chen WJ. Control of IFN-g production and regulatory function of Tregs by the inducible nuclear protein IkB-z in T cells Journal of Leukocyte Biology 98(3):385-93, 2015.

17. Kusaka T, Nakayama M, Nakamura K, Ishimiya M, Furusawa E, Ogasawara K. Effect of silica particle size on macrophage inflammatory responses. PLoS One. Mar 28;9(3):e92634. doi: 10.1371/journal.pone.0092634, 2014.

18. Kawano M, Nakayama M, Aoshima Y, Nakamura K, Ono M, Nishiya T, Nakamura S, Takeda Y, Dobashi A, Takahashi A, Endo M, Ito A, Ueda K, Sato N, Higuchi S, Kondo T, Hashimoto S, Watanabe M, Watanabe M, Takahashi T, Sasaki K, Nakamura M, Sasazuki T, Narushima T, Suzuki R, Ogasawara K NKG2D+ IFN-g+ CD8+ T cells are responsible for palladium allergy PLoS One Feb 12;9(2):e86810, 2014

19. Nakamura K, Nakayama M, Kawano M, Amagai R, Ishii T, Harigae H, Ogasawara K. Fratricide natural killer cells dressed with tumor-derived NKG2D ligand. Proc Natl Acad Sci USA 110 (23) : 9421-9426, 2013.

1. 小笠原康悦「アレルギーにおけるネオ・セルフ」第60回歯科基礎医学会学術集会 日本学術会議シンポジウム
「口腔と全身のネットワーク―免疫学の新機軸―」東京 2019.9.5-7

2. Ogasawara K “New TCR analysis for cancer Immunotherapy”
The 34th Nagoya International Cancer Treatment Symposium Feb.9-10, 2019

3. 小笠原康悦「金属アレルギー研究の最前線」東北矯正歯科学会 仙台2018 5.26-27 

1.標準免疫学 第4版 医学書院 2021年 執筆:小笠原康悦

Dept. Immunobiology IDAC,

Tohoku University東北大学 加齢医学研究所 生体防御学分野

TEL: 022-717-8579
FAX: 022-717-8822
mail: immunobiology(a)